1-Deoxy-d-arabinitol
نویسندگان
چکیده
Addition of methyl lithium to d-erythrono-1,4-lactone followed by acid deprotection was shown, by X-ray crystallography, to give 1-de-oxy-d-arabinitol, C(5)H(12)O(4), rather than 1-de-oxy-d-ribitol as the major product. The crystal structure exists as hydrogen-bonded chains of mol-ecules running parallel to the c axis which are further linked together by hydrogen bonds. Each mol-ecule is a donor and an acceptor for four hydrogen bonds.
منابع مشابه
A rapid, automated enzymatic fluorometric assay for determination of D-arabinitol in serum.
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A clinical study was carried out on 11 patients with Candida urinary tract infection; 4 with chronic cystitis and 7 with acute pyelonephritis including 2 patients associated with candidemia. The patients received 1.5 to 6.0 g of 5-fluorocytosine (5-FC) orally daily for 6 to 22 days. The response was excellent in 6, moderate in 4 and poor in 1 case, overall efficacy rate being 90.9%. No patients...
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عنوان ژورنال:
دوره 64 شماره
صفحات -
تاریخ انتشار 2008